A nurse is caring for a 4 year old child who has a new diagnosis of diabetes

Denis Daneman, MB BCh FRCPC,1,3 Marcia Frank, RN MHSc CDE,1 Kusiel Perlman, MD FRCPC,1,3 and Jean Wittenberg, MD FRCPC2,3

Denis Daneman

1Division of Endocrinology

3University of Toronto, Toronto, Ontario

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Marcia Frank

1Division of Endocrinology

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Kusiel Perlman

1Division of Endocrinology

3University of Toronto, Toronto, Ontario

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Jean Wittenberg

2Department of Paediatrics, and Department of Psychiatry, The Hospital for Sick Children and

3University of Toronto, Toronto, Ontario

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1Division of Endocrinology

2Department of Paediatrics, and Department of Psychiatry, The Hospital for Sick Children and

3University of Toronto, Toronto, Ontario

Copyright © 1999, Pulsus Group Inc. All rights reserved

Abstract

Infants and toddlers comprise a small minority of individuals with type 1 diabetes. However, epidemiological data provide evidence of a trend towards diagnosis at a younger age. These very young children pose significant challenges to both the health care professionals involved in their care as well as to their families. At diagnosis, younger children often do not present with classical symptoms of diabetes. Unless health professionals remain alert to the possibility of diabetes being the underlying cause of a child’s illness, the diagnosis may be missed. Once the diabetes has been diagnosed, the major challenge is to set up a treatment regimen that is both reasonable and realistic; in the youngest children, the goal of very tight metabolic control may expose them to episodes of severe hypoglycemia which may lead to subtle cognitive impairments later in life. The therapeutic regimen must balance the naturally erratic eating and exercise patterns of very young children with the need to maintain adequate metabolic control. Setting a blood glucose target range of 6 to 12 mmol/L usually allows this to be accomplished. Diabetes during early childhood creates a psychosocial challenge to the families of these children. Successful management of infants and toddlers with diabetes depends on a well functioning and educated family, the availability of diabetes health care team experienced in the treatment of these youngsters, and the involvement of the extended family, child care personnel and others who play a role in their daily care.

Keywords: Infants, Metabolic control, Toddlers, Type I diabetes

RÉSUMÉ :

Les nourrissons et les tout-petits représentent une infime minorité des diabétiques de type 1. Cependant, les données épidémiologiques démontrent une tendance vers un diagnostic plus précoce. Ces très jeunes enfants représentent des défis importants tant pour les professionnels de la santé qui participent à leurs soins que pour leur famille. Souvent, au moment du diagnostic, les enfants plus jeunes ne présentent pas les symptômes classiques du diabète. À moins que les professionnels de la santé ne gardent toujours en tête la possibilité de diabète comme cause sous-jacente d’une maladie de l’enfant, il est possible que le diagnostic passe inaperçu. Une fois le diagnostic posé, le principal défi consiste à établir un schéma thérapeutique à la fois raisonnable et réaliste. Chez les plus jeunes, un contrôle métabolique trop serré peut constituer un danger d’hypoglycémie grave pouvant entraîner des déficiences cognitives discrètes à l’âge adulte. Le schéma thérapeutique doit équilibrer les tendances d’alimentation et d’exercice erratiques naturelles des tout-petits avec le besoin de maintenir un contrôle métabolique convenable. Il est généralement possible d’y parvenir en se donnant comme objectif une glycémie de 6 mmol/l à 12 mmol/l. Par ailleurs, le diabète pendant la première enfance représente un défi psychosocial pour les familles de ces enfants. La prise en charge des nourrissons et des tout-petits diabétiques ne réussira que si la famille fonctionne bien et est bien informée, si une équipe habituée aux soins des très jeunes diabétiques est disponible et si la famille élargie, les éducateurs et les autres personnes qui participent aux soins quotidiens des ces enfants y mettent du leur.

Children under three to five years of age with type I diabetes comprise a small proportion of all those with this disorder: less than 1% of all children are diagnosed in the first year of life, and less than 2% of children attending large paediatric diabetes centres fall into the under three-year age group. Nevertheless, recent experience, backed up by epidemiological studies, suggests a significant trend towards diagnosis of type I diabetes at a younger age (1).

Infants and toddlers with diabetes pose a series of important challenges to health care professionals. First, at the time of diagnosis, children often do not present with the classical early symptoms and signs of diabetes. Second, it is difficult to set up an appropriate therapeutic regimen for them. Third, it is a challenge to prevent serious hypoglycemia, which is especially important given hypoglycemia’s potential impact on the developing brain. Finally, from the psychosocial standpoint, there is the impact that a serious chronic disorder can have on the child and family. In this article, we will focus on these major issues, highlighting the need to balance what may be thought of as ideal care in older individuals with diabetes with what is practical and realistic in infants and toddlers.

DIAGNOSING DIABETES IN VERY YOUNG CHILDREN

When a sick infant or toddler presents to their primary care physician, type I diabetes is generally not high on the list of possible diagnoses, given the relatively low incidence of the disease in this age group. Furthermore, the classical symptoms of polyuria and nocturia, polydipsia, polyphagia, and weight loss are often overlooked or ascribed to other causes until the disorder has progressed to frank diabetic ketoacidosis (DKA). Even then the diagnosis may not be made immediately, and other serous illnesses such as bronchiolitis or asthma (because of the ‘heavy’ Kussmaul breathing), or meningitis or septicemia (associated with obtundation and severe dehydration) may be considered first. The presence of a candida diaper dermatitis (and particularly one that is resistant to therapy) may provide a significant tip-off of the presence of glycosuria.

It is the authors’ clinical impression that many infants and toddlers are seen multiple times by one or more physicians or other health care professionals before ‘the penny drops’. The presence of polyuria and polydipsia may not only be overlooked, but may also be used to reassure the parents that nothing can be terribly wrong if their child is drinking and urinating well. The diagnosis may be one of upper respiratory infection or otitis media, or urinary tract infection if the excess urination is noted. It is not uncommon for children to receive a series of antibiotics for an illness that is not responding to treatment. For this reason, it is recommended that all infants and toddlers presenting to their physician with an illness for which there is not another readily acceptable explanation undergo a simple urinalysis to exclude glycosuria and ketonuria (2). Although diabetes is diagnosed in only a very small minority of such children, its detection prevents the development of severe DKA, the morbidity associated with severe dehydration or shock in an infant or toddler and the need for more prolonged hospitalization.

Of note is that some young children who are given large volumes of fruit juice and other concentrated carbohydrate-containing fluids in response to the polydipsia may present with severe degrees of hyperglycemia (greater than 50 mmol/L) and hyperosmolality (greater than approximately 350 mOsm/kg). Extreme caution should be exercised in correcting the DKA and hyperosmolar state to prevent a rapid drop in serum osmolality and possible intracranial fluid shifts (3,4).

ONCE THE DIAGNOSIS HAS BEEN MADE

Traditionally, most children with new onset type I diabetes, and particularly the youngest ones, have been hospitalized to stabilize their hyperglycemia and to provide the initial education of their families. In more recent years, there has been a trend away from hospitalization at diagnosis except under certain circumstances (5,6). The Hospital for Sick Children has found this to be no less true for infants and toddlers than for older children and teens. Indications for hospitalization include the severity of their condition at diagnosis (eg, DKA, hyperosmolality), family living far from the hospital with difficulty attending on a daily basis, or if the responsible physician is not certain that the family understands the significance of the diagnosis or may be unlikely to attend the day care education program. The latter may be due to the presence of a language barrier or part of a severe emotional response to the diagnosis.

The authors’ approach to the immediate postdiagnosis management of these infants and toddlers is as follows. If admitted, children should remain in hospital only as long as their clinical condition demands (usually less than two to four days). If the child is not hospitalized, the family should return on a daily basis for two to four days to the diabetes day care facility: they arrive before breakfast and leave after dinner each day. During this time, parents and/or other primary caregivers are taught the ‘survival skills’ needed to care for an infant or toddler with diabetes, ie, insulin injection technique, blood glucose monitoring, appropriate infant feeding, and recognition and treatment of hypoglycemia. More complete diabetes education is carried out on an ambulatory basis as the family begins to deal with the diabetes at home; this is invariably accomplished within two to four weeks of diagnosis. Throughout this early phase, general medical care and psychosocial support are provided by a core diabetes team experienced in the care of young patients, including a paediatric endocrinologist, diabetes nurse, dietitian and social worker. It is often beneficial to have home care providers assist the family with the routines after their initial period in day care.

INSULIN

Whether hospitalized or not, infants and toddlers are given very small doses of intermediate- (usually NPH) and fast- or super-fast-acting (either regular or insulin lispro, Humalog, Eli Lilly Canada) human insulins given twice daily. In the youngest infants, particularly those who are still breastfeeding, the injections are given about 12 h apart (about 08:00 and 20:00) and in the older children before breakfast and supper. As the children grow older, they are switched to a three-times daily injection routine with NPH and Regular/insulin lispro at breakfast, Regular/insulin lispro at supper and NPH at bedtime.

The authors usually start with about 0.25 to 0.5 U of insulin/kg body weight per day with the larger dose (about two-thirds) given in the morning, and about two-thirds to three-quarters of each dose given as NPH insulin, the remainder as Regular or insulin lispro. This is preferred to half- or full unit dosages and avoids the need for dilution of the insulin. The dose is slowly but steadily increased (by no more than 1 to 2 U each day) until blood glucose concentrations start to fall into the target range (6 to 12 mmol/L before meals, see below). This approach minimizes the risks of early hypoglycemia events while the family is still learning the ins and outs of diabetes management. Using this approach, the authors are unaware of any severe hypoglycemia episodes occurring in these young children in the first year after diagnosis (7).

Many parents of infants and toddlers with diabetes have concerns about giving insulin before they know how much their child is going to eat. This is especially true in those labelled as ‘picky eaters’. It is in these children that the superfast-acting insulin analogue, insulin lispro, may be most appropriate: the parents can judge the amount of food eaten at the meal and then give the insulin dose immediately afterwards. This approach requires that the parents become quite adept at judging the amount of food eaten and deciding on the appropriate amount of insulin based on an insulin dose algorithm or ‘sliding scale’.

The authors recommend insulin dosage adjustments based on ‘pattern management’. If blood glucose levels exceed the upper limit of the target range for three days in a row, the appropriate insulin dose is increased by 0.5 to 1 U at a time; if the levels are below the lower limit of the target range for two days in a row, the insulin is decreased by a similar amount. While most families use this pattern management approach, many are also taught how to make minor adjustments in the Regular or insulin lispro dose before breakfast and supper, depending on the ambient blood glucose level at that time and, in those receiving postprandial insulin lispro, the size of the meal.

Infants and toddlers require proportionately lower doses of insulin than older children or adolescents do (8). This demands that care be taken when adjusting the dosage of these preparations. For those few infants in whom single or even half unit doses cause hypoglycemia, dilution of the insulin may be necessary to deliver a reproducible amount. There are some data to suggest that diluted insulins may be less predictably absorbed.

In some centres, even infants and toddlers are placed on a multiple daily insulin injection regimen, with small doses of Regular or insulin lispro insulin given before each meal, and NPH either once (at bedtime) or twice (at both breakfast and bedtime) daily. There are no data available as to whether this approach provides improved metabolic control and/or a lower frequency of hypoglycemia. We are concerned about the added burden placed on the child and family by such an intensive approach at such a young age.

MONITORING AND THE TARGET RANGE

Blood glucose monitoring is an especially useful tool in the management of the youngest children with diabetes; no longer do parents need to squeeze out their child’s diapers to test his or her urine! The authors have found that the families of most infants and toddlers are willing to test their children’s glucose levels three, four or more times a day to maintain control of the diabetes and to feel confident that the child is safe. The authors’ recommend that this monitoring be performed before meals and at the time of the bedtime snack. Additional testing 2 h after this snack or in the middle of the night (eg, 24:00 to 04:00) is also useful at times to predict and prevent nocturnal hypoglycemia.

Most families find that it is more convenient to use glucose meters than to determine glucose concentrations with visual strips. While most of the meters provide an excellent degree of accuracy and are relatively user friendly, the families of the infants and toddlers usually prefer meters that require smaller amounts of blood for test performance and those that can be moved to accept the drop of blood rather than requiring the child’s finger to be in the correct position.

While studies such as the Diabetes Control and Complications Trial (DCCT) have unequivocally demonstrated a close relationship between the level of metabolic control achieved over the long term, and the onset and progression of the chronic microvascular complications of diabetes, none has included a prepubertal cohort (9,10). There are also data that, although still controversial, suggest that the clock does not start ticking (or at least ticks more slowly) in children with diabetes before the onset of puberty (11,12). Furthermore, there are also data (see the section on Hypoglycemia) that demonstrate that infants and toddlers who experience severe hypoglycemia early in the course of their diabetes may be at risk for subtle cognitive impairment later in life (13–15). It is for these reasons that a safe and realistic target range for blood glucose and hemoglobin A1c (HbA1c) levels should be set for young children. It is suggested that a range of blood glucose concentrations from 6 to 12 mmol/L (approximately 110 to 220 mg/dL) before meals and snacks is both achievable and safe in most infants and toddlers. This contrasts with a target of 4 to 10 mmol/L in school-aged children, and 4 to 7 or 8 mmol/L in adolescents. The target should represent the range in which most (perhaps 60% to 75%) of the blood glucose concentrations fall. It is impossible for all values to fall within this relatively narrow range.

Achievement of blood glucose levels in this target range should to lead to HbA1c levels below 8.5% to 9% (where the nondiabetic range is 4% to 6%). Levels of 8.5% to 9% should lead to appropriate adjustments in the treatment regimen to improve metabolic control. As diabetic children grow, tighter blood glucose and HbA1c targets become more realistic. Conversely, HbA1c levels close to the nondiabetic range in these infants and toddlers demand that parents keep a very close watch for possible undetected hypoglycemia.

While the emphasis of home monitoring is on the measurement of blood glucose concentrations, families should also be taught how to test for urine ketones. These should be checked during episodes of intercurrent illness (see section on Sick Days) and if glucose levels fall above the target range for three or more tests in a row. This added information is useful for making appropriate adjustments to the insulin dosage. The presence of an intercurrent illness with high blood glucose concentrations and ketones in the urine is a strong signal for concern.

MEAL PLANNING

All families should have access to a dietitian who is experienced in infant nutrition as well as in diabetes care. For infants and toddlers with diabetes, the emphasis should be placed, initially at least, on teaching the principles of good infant nutrition with the provision of a variety of foods at consistent times and in fairly consistent amounts. There should also be some limitation put on the amount of concentrated carbohydrate (usually in the form of fruit juices) offered. For the majority of families with infants and toddlers with diabetes, this approach will suffice. Infants and toddlers often have erratic eating patterns: some days they seem to want to eat everything in sight and on other days they are content to pick at the food on their plate. For these families, a more formal diabetes meal plan (based either on an exchange-type diabetes diet or on carbohydrate counting) can be introduced once the child has a more structured lifestyle (eg, when starting school).

Parents should be advised to try not to fight with their children at meal times, and not to try to force feed those who do not finish their portions. Furthermore, parents should also avoid letting meal times drag on indefinitely –they will soon feel that their entire day revolves around food preparation and eating. In general, children will eat when they are hungry. Parents should use the results of blood glucose testing to direct their actions around offering food.

For some families, a more structured meal plan may be beneficial even at a young age, particularly if the family is anxious about the portion sizes that they are providing or if they are adjusting their insulin lispro insulin dose based on the amount of food eaten at the meal. A clearly structured meal plan may sometimes help avoid costly and unnecessary conflicts around feeding.

PHYSICAL ACTIVITY

Physical activity in general increases glucose utilization and lowers blood glucose concentrations. Although this has the potential for a beneficial effect on overall blood glucose control, exercise should not be regarded as one of the cornerstones of diabetes management but rather as an integral component of healthy living. Activity should be taken into consideration when making adjustments in the treatment regimen.

Most diabetic infants and toddlers are as active as can be expected for their developmental stage; however, this can vary considerably from day to day. There is nothing that can be done or should be done to prevent this variability. Rather, as children grow, they should be encouraged to participate in physical activities; they learn best by example. If toddlers participate in additional activities (eg, play school, swimming lessons, etc), an extra snack should be provided and their blood glucose checked more frequently to determine the effect of the activity on their diabetes control. Future adjustments in the diabetes regimen can then be planned on the basis of these experiences.

HYPOGLYCEMIA

There are three issues of importance with respect to hypoglycemia in this age group. First, there are data showing that younger children with diabetes are more likely to experience severe hypoglycemia than are older children and teens (16,17). Second, infants and toddlers are invariably unable to express themselves in such a way that their parents can be certain that their symptoms are those of a hypoglycemic event. Third, repeated hypoglycemic episodes put them at risk for the later development of subtle cognitive or learning impairment (13–15).

The early warning symptoms of hypoglycemia in infants and toddlers with diabetes may be quite subtle: behavioural change (eg, irritability, crankiness, lethargy or floppiness, temper tantrums), sweating, pallor, a ‘different’ kind of cry or waking up at night crying. If not dealt with quickly, this may lead to severe hypoglycemia with coma or convulsion. Because it may be difficult to determine whether a certain behaviour on a specific day represents hypoglycemia, it is imperative that parents or other care providers monitor blood glucose levels at these times to confirm (or reject) hypoglycemia and direct treatment. The presence of a blood glucose level below 6 mmol/L in the presence of symptoms should lead to provision of about 60 to 120 mL of juice. If the episode occurs immediately before a meal, the meal should be started at once and the simple carbohydrate offered first.

Care should be taken not to overtreat mild hypoglycemia: there is often a tendency for parents to want to offer as much food as possible until the symptoms abate. This will inevitably lead to rebound hyperglycemia. Rather, the parent should offer the child 60 to 120 mL of juice and then wait 10 to 15 mins. If the symptoms continue, the treatment should be repeated. Reactions that occur during the night should be treated with a bottle or glass of milk. An alternative is to provide some juice plus a source of complex carbohydrate (eg, cookies) to support the blood glucose overnight.

All families of children with diabetes should have a Glucagon Emergency Kit at home to treat severe hypoglycemia (18). The authors have found that using 0.5 mg (equal to 0.5 mL of the reconstituted glucagon) in children under five to six years of age rapidly reverses hypoglycemia. In many such instances, either the hypoglycemic event itself or the use of glucagon may trigger vomiting. If this occurs, the child should be taken to the nearest hospital emergency room for intravenous glucose therapy until the vomiting stops.

The reason to avoid severe hypoglycemia at all costs relates to the risk of later cognitive deficits. Ryan and Rovet and their colleagues (13–15) have shown that the children with diabetes who develop hypoglycemia during their period of brain growth (younger than approximately three years of age) are at most risk for these subtle deficits during adolescence.

‘SICK DAYS’

Infants and toddlers with type I diabetes are no more likely than their nondiabetic peers to develop other acute illnesses. Nevertheless, children in this age group do tend to develop frequent minor respiratory and gastrointestinal illnesses that may play havoc with their diabetes. Significant illness generally creates a stress situation with increased counter-regulatory hormone production, and the risk of hyperglycemia and DKA. On the other hand, if the illness interferes with food intake, the child may be at risk for serious hypoglycemia. It is for these reasons that the family should follow a few simple rules once an intercurrent illness develops (Tables 1, ,2)2) (19).

TABLE 1:

‘Sick day’ rules for young children with diabetes

  • Check blood glucose concentration and urine ketones every 4 h around the clock.

  • Make sure that the child continues to receive fluids and calories; if the child is unable to eat, offer clear glucose-containing fluids (eg, juice, ginger ale, Jell-o or popsicles).

  • Do not discontinue insulin: the dose may need to be adjusted.

  • Treat the underlying illness. The effect on metabolic control will not be alleviated until the illness resolves or is treated.

  • Call the diabetes team immediately or go the nearest emergency room if

    • the child refuses to eat, drink or vomits more than twice in a short space of time;

    • the blood glucose concentration remains low despite appropriate food intake and insulin doses adjustment; or

    • the blood glucose remains high with positive urinary ketones despite appropriate illness management.

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TABLE 2:

Insulin dose adjustment during ‘sick days’

IfThenBlood glucose remains more than 6 mmol/L but less than 13 mmol/LContinue the same dose independent of urine ketones.Blood glucose is greater than 13 mmol/L but less than 17 mmol/L AND ketones are absentStart the next day to increase dose 10% to 20% per day until target sugars are achieved.Blood glucose remains greater than 13 mmol/L AND ketones are moderate or large, OR blood glucose is greater than 17 mmol/L independent of ketonesGive extra Regular/insulin lispro immediately: approximately 10% to 20% of daily dose every 4 h until glucose is less than 13 mmol/L and ketones are negative to small.Blood glucose less than 6 mmol/LEncourage glucose-containing fluids

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PSYCHOSOCIAL ISSUES

Each age and stage of life present a different set of challenges concerning physical and emotional growth and development. The addition of a chronic disorder such as diabetes can increase the magnitude of many of these challenges considerably. Studies of the psychosocial adaptation to diabetes have focused largely on children over eight years of age: Kovacs and her colleagues (20–22) and others (23,24) have followed a cohort of children diagnosed between eight and 13 years of age, while Jacobson’s group (23,24) comprised children age nine to 16 years at diagnosis. Both major longitudinal studies of adaptation to diabetes demonstrate that many of these children and their families have considerable difficulties in the immediate postdiagnosis phase, followed by a ‘settling down’ or coping phase and then a significantly increased potential for problems after many years (22,25). Although it is reasonable to hypothesize that similar outcomes would be found in the very youngest children with diabetes, there are no empirical data to either support or refute this viewpoint.

Experience, supported by a single qualitative study (26), suggests that both medical and psychosocial factors pose an increased burden to the family during infancy and early childhood, and may predispose the family to both family dysfunction and difficulties with achieving good metabolic control in the child. The combined risk of severe hypoglycemia and its impact on the developing brain (13–15), and the erratic eating and activity patterns of infants and toddlers makes adjustment of the treatment regimen more difficult.

From the available studies in older children (20–24), it is clear that diabetes is a significant burden to the family and child: important associations have been reported between maternal and child psychopathology (26) and between maternal and child depression (27). Family behaviours (28) and characteristics, such as organization and cohesiveness, emotional expressiveness, lower levels of conflict and more marital satisfaction in the parents (29,30), have been associated with better metabolic control in the child, particularly in the younger children in these studies. Furthermore, the family environment was strongly related to perceived competence and self-esteem, diabetes adjustment and symptomatology in the older children (31).

There is evidence that periods of major psychological transition are associated with increased vulnerability. Adolescence is such a transition and has been well studied. On the other hand, the first three years of life are also recognized as a time of rapid change and development with long-lasting implications for the future (32). It would be surprising if diabetes and its management in this period did not have the potential to influence development significantly.

Diabetes and its management impinge on the normal psychological tasks of infancy and early childhood, including developing a sense of one’s own body (which includes appetites and preferences) (33) and establishing a sense of trust and security in one’s caregivers, especially at times of pain distress (34). Parents and other primary caregivers who are needed as sources of security and comfort become agents of pain: the child is subjected repeatedly to insulin injections, finger pricks and an increase in the external control of diet preferences and food intake. Additionally, if parents are distressed by frequent reminders of their child’s diabetes, they may compromise their ability to offer comfort and security to their youngsters when they need it most.

Food intake is a potentially contentious issue for parents and infants or toddlers, even in the absence of diabetes. Up to 25% of all young children may have feeding difficulties at some time (35). In other disorders where feeding is of special interest, such as cystic fibrosis, the rates of feeding disorders are increased (36). Hypoglycemic events cause special concern to parents, given their potential to affect later cognitive impairment (13–15) and because they are hard to identify (25). Thus, it seems likely that parents of infants and toddlers with diabetes will become engaged in struggles over eating at least as commonly, if not more so, than do parents of nondiabetic children.

The authors believe that the onset of diabetes during early childhood poses a definite risk of the development of significant family dysfunction, maladaptive behaviour and poor metabolic control in the children and their families. The authors suspect that the presence and severity of such dysfunction and behaviour depend highly on family adaptation before onset of diabetes and on the early psychosocial responses following diagnosis. It is also suspected that adaption to diabetes will be affected by early experiences such as hypoglycemia and DKA. Clearly, research is urgently needed about the early adaptation of these children and their families, with the aim of finding interventions to lessen the negative outcomes in some families.

HELPFUL HINTS IN COPING WITH INFANTS AND TODDLERS WITH DIABETES

Adopt a ‘matter-of-fact’ approach to the routines (injections, finger pricks and meal times) and maintain an emotionally positive attitude throughout. Young children quickly pick up on the anxieties of their parents and are likely to be distressed in response. Children may show oppositional or withdrawal behaviour even while their parents are trying to reassure them. This may be disconcerting and upsetting for the parents. A vicious cycle may ensue in that the more the parents try to console the child and coax him or her to have an injection or finger prick, the more oppositional or withdrawn the child may become. Parents can learn to master interactions and modulate their own behaviours if they recognize these situations as opportunities to teach their children, and if they understand that their child learns from everything the parents say or do.

Prepare the insulin or blood testing equipment in another room out of sight of the infant or toddler and only involve him or her once everything is ready. This may shorten his or her period of anxiety or upset considerably.

Involve the whole family. Diabetes care is a partnership between the child with diabetes and the whole family. Parents should share the responsibility for the diabetes care to prevent the child from playing one off against the other. In single parent families, enlisting support from extended family members, friends or home care professionals may help to lessen the stress for parents.

If the child is upset by the injections or finger pricks, try distractions, such as signing songs, holding a favourite animal or toy, or watching television while the routine is performed. Then give the child a hug and a kiss, and move on with the day. Find ways to give the child some control over aspects of these otherwise unpleasant procedures, eg, do not give the injection until she or he is holding her or his favourite teddy bear. Provide reassurance throughout and try not to express anger; it is normal for children to refuse or resist needles or finger pricks.

For the really picky eater, set limits on the amount of time for meals and snacks. If they have not eaten in the allotted time, take the food away. Parents should offer healthy foods that their child usually enjoys. Parents must then understand that their child eats best when he or she pays attention to his or her feelings of hunger and satiety. Begging children to eat or force feeding them will interfere with that awareness. Regular blood glucose checks will prevent hypoglycemia.

Use the resources available: the diabetes team, in particular, but also parent support groups, volunteer agencies (eg, the Canadian Diabetes Association), etc.

CONCLUSIONS

The family of the infant or toddler with type I diabetes is faced with a long and seemingly arduous journey through early childhood, the school years and adolescence before the child establishes him- or herself as an independent young adult. At times this path may seem like a minefield to many parents. They should take heart: the vast majority of children carefully and successfully manoeuvre their way through the age and stage transitions, and learn to cope with and adjust to their diabetes. Success depends on a well functioning and fully informed family, an available and experienced diabetes health care team, and the involvement of the extended family, day care personnel and others who play a role in the child’s day-to-day care. With this support and guidance, the burden of diabetes can be significantly reduced.

REFERENCES

1. Gardner SG, Bingley PJ, Sawtell PA, Weeks S, Gale EAl. Rising incidence of insulin-dependent diabetes in children aged under 5 years in the Oxford region: time trend analysis. The Bart’s-Oxford Study Group. Br Med J. 1997;315:712–7. [PMC free article] [PubMed] [Google Scholar]

2. Frank M, Link J, Daneman D, Perlman K, Ehrlich RM. The young child with diabetes: Challenges of diagnosis and management. Clin Diabetes. 1986;4:121–40. [Google Scholar]

3. Rubin HM, Kramer R, Drash A. Hyperosmolality complicating diabetes mellitus in childhood. J Pediatr. 1969;74:177–86. [PubMed] [Google Scholar]

4. Bain H, Ehrlich RM. Hyperosmolar non-ketotic coma. Lancet. 1967;ii:1258. [PubMed] [Google Scholar]

5. Swift PG, Hearnshaw JR, Botha JL, Wright G, Raymond NT, Jamieson KF. A decade of diabetes: keeping children out of hospital. Br Med J. 1993;307:96–8. [PMC free article] [PubMed] [Google Scholar]

6. Chase HP, Crews K, Gary S, et al. Outpatient management vs in-hospital management of children with new-onset diabetes. Clin Pediatr (Phila) 1992;8:450–6. [PubMed] [Google Scholar]

7. Daneman D, Frank M. Defining quality of care in type I diabetes. Acta Paed Scand. 1998;(Suppl 425):11–19. [PubMed] [Google Scholar]

8. Pontius SL. Diabetes mellitus and the preschool child. In: Haire-Joshu D, editor. Management of Diabetes Mellitus: Perspectives of Care Across the Life Span. 2nd edn. St Louis: Mosby Yearbook Publishers; 1996. pp. 579–634. [Google Scholar]

9. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med. 1993;329:977–86. [PubMed] [Google Scholar]

10. Effect of intensive diabetes treatment on the development and progression of long-term complications in adolescents with insulin-dependent diabetes mellitus: Diabetes Control and Complications Trial. Diabetes Control and Complications Trial Research Group. J Pediatr. 1994;125:177–88. [PubMed] [Google Scholar]

11. Lawson M, Sochett EB, Chait PG, Balfe JW, Daneman D. Effect of puberty on markers of glomerular hypertrophy and hypertension in diabetes. Diabetes. 1996;45:51–5. [PubMed] [Google Scholar]

12. Kastraba JN, Dorman JS, Ochard TJ, et al. Contribution of diabetes duration before puberty to development of micro vascular complications in IDDM subjects. Diabetes Care. 1989;12:686–93. [PubMed] [Google Scholar]

13. Ryan C, Vega A, Drash A. Cognitive deficits in adolescents who developed diabetes early in life. Pediatrics. 1985;75:921–7. [PubMed] [Google Scholar]

14. Rovet JE, Ehrlich RM, Hoppe M. Intellectual deficits associated with early onset insulin-dependent diabetes mellitus in children. Diabetes Care. 1987;10:510–5. [PubMed] [Google Scholar]

15. Rovet JE, Ehrlich RM, Czuchka D, et al. Psychoeducational characteristics of children and adolescents with insulin-dependent diabetes mellitus. J Learn Disabil. 1993;26:7–22. [PubMed] [Google Scholar]

16. Daneman D, Frank M, Perlman K, Tamm J, Ehrlich R. Severe hypoglycemia in children with insulin-dependent diabetes mellitus: Frequency and predisposing factors. J Pediatr. 1989;109:681–5. [PubMed] [Google Scholar]

17. Mortensen HB, Hoogarrd P, Hvidore Study Group on Childhood Diabetes Comparison of metabolic control in a cross-sectional study of 2873 children and adolescents with insulin-dependent diabetes from 18 nations. Diabetes Care. 1997;20:714–20. [PubMed] [Google Scholar]

18. Daneman D, Frank M. Glucagon: What it is and when should it be used? Diabetes Forecast. 1998;51:44–8. [Google Scholar]

19. Daneman D, Frank M. Managing intercurrent illness in the child with insulin-dependent diabetes mellitus. Clin Diabetes. 1984;2:1–7. [Google Scholar]

20. Kovacs S, Feinberg TL, Paulaskas S, Finkelstein R, Pollock M, Crouse-Novak M. Initial coping responses and psychosocial characteristics of children with insulin-dependent diabetes mellitus. J Pediatr. 1985;106:827–34. [PubMed] [Google Scholar]

21. Kovacs M, Finkelstein R, Feinberg TL, Crouse-Novak M, Paulauskas S, Pollock M. Initial psychological response of parents to the diagnosis of insulin-dependent diabetes in their children. Diabetes Care. 1985;8:568–75. [PubMed] [Google Scholar]

22. Kovacs M, Obrosky DS, Iyengar S. Prevalence and predictors of pervasive noncompliance with medical treatment among youths with insulin-dependent diabetes mellitus. J Am Acad Child Adolesc Psychiatr. 1992;31:1112–9. [PubMed] [Google Scholar]

23. Jacobson AM, Hauser ST, Lavori P, et al. Adherence among children and adolescents with insulin-dependent diabetes mellitus over a four year longitudinal follow-up: I Influence of patient coping and adjustment. Pediatr Psychiatr. 1990;15:511–26. [PubMed] [Google Scholar]

24. Jacobson AM, Hauser ST, Willett JB, et al. Psychological adjustment to IDDM: 10-year follow-up of an onset cohort of child and adolescent patients. Diabetes Care. 1997;20:811–8. [PubMed] [Google Scholar]

25. Kovacs M, Goldston D, Obrosky DS, Bonar LK. Psychiatric disorders in youth with IDDM: Rates and risk factors. Diabetes Care. 1997;20:36–44. [PubMed] [Google Scholar]

26. Hatton DL, Canam C, Thorne S, Hughes A-M. Parent’s perception of caring for infant or toddler with diabetes. J Advanced Nursing. 1995;22:569–77. [PubMed] [Google Scholar]

27. Mullins LL, Chaney JM, Hartman VL, et al. Child and maternal adaptation to cystic fibrosis and insulin-dependent diabetes mellitus. Different patterns across disease states. J Pediatr Psychol. 1995;20:173–86. [PubMed] [Google Scholar]

28. McKelvey J, Waller DA, Stewart SM, Kennard BD. Family support for diabetes: a pilot study measuring disease-specific behaviours. Children’s Health Care. 1989;18:37–41. [Google Scholar]

29. Marteau TM, Bloch S, Baum JD. Family lives and diabetes control. J Psychol Psychiatr Allied Disciplines. 1987;28:823–33. [PubMed] [Google Scholar]

30. Hauser ST, Jacobson AM, Lavori P, et al. Adherence among children and adolescents with insulin-dependent diabetes mellitus over a four-year longitudinal follow-up: II Immediate and long-term linkages with the family milieu. J Pediatr Psychiatr. 1990;15:527–42. [PubMed] [Google Scholar]

31. Hauser S, Jacobson JM, Wertlieb D, Blank J, Wentworth S. The contribution of family environment to perceived competence and illness adjustment and acutely-ill adolescents. Family Relations. 1985;134:99–108. [Google Scholar]

32. Goldberg S. Recent developments in attachment theory and research. Can J Psychiatr. 1991;36:393–400. [PubMed] [Google Scholar]

33. Stern D. The Interpersonal World of the Infant. New York: Basic Books; 1995. [Google Scholar]

34. Bowlby J. Attachment and Loss. Attachment. Vol. 1. New York: Basic Books; 1973. [Google Scholar]

35. Babbit RL, Hoch TA, Coe DA, et al. Behavioral assessment and treatment of feeding disorders. J Dev Behav Pediatr. 1994;15:278–91. [PubMed] [Google Scholar]

36. Crist W, MacDonnell P, Beck M, Gillespie CT, Barrett P, Matthews J. Behavior at mealtimes and the young child with cystic fibrosis. J Dev Behav Pediatr. 1994;15:157–61. [Google Scholar]

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  • Infants and toddlers with diabetes

Paediatr Child Health. 1999 Jan-Feb; 4(1): 64.

Infants and toddlers with diabetes

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Answer the following questions by circling the letter of the correct answer(s). Answers can be found on page 86.

How to Test kids for diabetes?

Your child will need to fast overnight and then drink a sugary liquid at the health care provider's office or a laboratory testing site. Blood sugar levels are tested periodically for the next two hours. A blood sugar level of 200 mg/dL (11.1 mmol/L ) or higher generally means your child has diabetes.

Which of the following indicates a client has diabetes?

A level of 200 mg/dL (11 mmol/L) or higher often means you have diabetes. Your provider will order a fasting blood glucose, A1C test , or glucose tolerance test , depending on your random blood glucose test result.

What is the symptoms of hypoglycemia?

Common symptoms may include:.
Fast heartbeat..
Shaking..
Sweating..
Nervousness or anxiety..
Irritability or confusion..
Dizziness..
Hunger..

What is diabetes simple explanation?

With diabetes, your body doesn't make enough insulin or can't use it as well as it should. When there isn't enough insulin or cells stop responding to insulin, too much blood sugar stays in your bloodstream. Over time, that can cause serious health problems, such as heart disease, vision loss, and kidney disease.